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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGDS All Species: 8.48
Human Site: T154 Identified Species: 18.67
UniProt: P41222 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41222 NP_000945.3 190 21029 T154 T L Y S R T Q T P R A E L K E
Chimpanzee Pan troglodytes XP_001168528 325 34672 P209 M C K S V V A P A A D G G L N
Rhesus Macaque Macaca mulatta XP_001091839 190 20992 T154 T L Y S R T Q T P R A E L K E
Dog Lupus familis XP_548441 198 22874 E163 T L Y G R T K E L P L E L K K
Cat Felis silvestris
Mouse Mus musculus O09114 189 21048 T154 T L Y S R T Q T L K D E L K E
Rat Rattus norvegicus P22057 189 21283 L154 T L Y S R A Q L L K E E L K E
Wallaby Macropus eugenll Q29614 174 20201 R139 M A C A H Y V R R I E E N K G
Platypus Ornith. anatinus XP_001516011 215 23425 L180 G N F N M A V L Y G R S Q D L
Chicken Gallus gallus NP_989590 185 20825 V149 L Y S R T K E V A P Q R L E R
Frog Xenopus laevis NP_001081513 184 20909 L149 L F G R D K D L R P E L L D K
Zebra Danio Brachydanio rerio NP_998799 184 20887 E148 K L Y S R T P E M V D D L K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.1 94.2 37.3 N.A. 71.5 68.4 21.5 30.7 43.1 40 30 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.5 95.7 53.5 N.A. 83.6 80.5 38.9 47.9 60 63.6 50.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 53.3 N.A. 80 66.6 13.3 0 6.6 6.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 66.6 N.A. 86.6 73.3 20 13.3 20 13.3 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 19 10 0 19 10 19 0 0 0 0 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 0 28 10 0 19 0 % D
% Glu: 0 0 0 0 0 0 10 19 0 0 28 55 0 10 46 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 0 0 0 0 10 0 10 10 0 10 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 19 10 0 0 19 0 0 0 64 19 % K
% Leu: 19 55 0 0 0 0 0 28 28 0 10 10 73 10 10 % L
% Met: 19 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 10 % N
% Pro: 0 0 0 0 0 0 10 10 19 28 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 37 0 0 0 10 0 10 0 0 % Q
% Arg: 0 0 0 19 55 0 0 10 19 19 10 10 0 0 10 % R
% Ser: 0 0 10 55 0 0 0 0 0 0 0 10 0 0 0 % S
% Thr: 46 0 0 0 10 46 0 28 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 10 19 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 55 0 0 10 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _